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The recommended dosage for rectally adults and adolescents with body weight over 60 kg is a single dose of 500 mg, the diversity of admission – up to 4 times / Maximum duration of treatment – 5-7 days. Maximum dose at single – 1 g, daily – 4 g. Single-dose for oral administration for children aged 6-12 years is at 250-500 mg, 1-5 years – 120-250 mg, from 3 months to 1 year – 60-120 mg, up to 3 months – 10 mg / kg. Single-dose rectal in children aged 6-12 years is at 250-500 mg, 1-5 years – 125-250 mg. Multiplicity – 4 at intervals of not less than four h. The maximum duration of treatment – 3 days.
Tempol is a synthetic compound that may be used to decrease pressure, prevent oxidative harm, and improve coronary heart disorder and diabetes. Tempol, additionally called four-Hydroxy-tempo, is a potent, synthetic compound that mimics the superoxide dismutase enzyme. The enzyme enables the boom rate of turning the superoxide radical into oxygen or hydrogen peroxide.
Tempol acts as an antioxidant because it is a Nitroxide. It may defend the mobile towards dealers that reason oxidative strain, which includes hyperoxide, hydrogen peroxide, and ionizing radiation. The mechanism of motion may be thru superoxide dismutase mimic activity.
Tempol protects against radiation and is used as a chemical antioxidant. Tempol restores the outcomes of TNF-alpha, that is worried in immune feature and acute irritation. Tempol could be very much like pace; however, it is greater appealing because it is inexpensive. It can enhance diseases as a result of oxidative strain, especially diabetes and illnesses related to diabetes, which includes high blood pressure, coronary coronary heart ailment, and nephropathy.
Tempol Reduces Oxidative strain, oxygen molecules with unpaired electrons are tremendously reactive and can reason numerous harm by way of chemically reacting with mobile components and inflicting destabilization.
Tempol May Help Diabetic Patients by the loose fatty acids that bind to GPR120, a type of G Protein-Coupled Receptor. This controls anti-inflammatory and insulin-sensitizing outcomes. Enhancing the G Protein-Coupled Receptor additionally permits for elevated insulin sensitivity. Thus, Tempol may have the ability to treat and to prevent symptoms associated with Type 2 Diabetes.
Research suggests that oxidative stress plays a function within the improvement of high blood pressure. High blood pressure also contributes to the development of renal failure, cardiovascular illnesses, obesity, and stroke.
Mice that had been fed high-fat diets and given Tempol had lower blood glucose and insulin tiers than mice that were not given Tempol. Mice, which acquired Tempol, did not advantage as a lot of weight as mice without Tempol. Tempol can affect the intestine and might treat both weight problems and diabetes.
A study on tempol impacted gut bacteria may lead to new treatments for obesity was conducted where the researchers dissolved the tempol in drinking water or added it directly to the mice. Within three weeks, tempol reduced the load advantage for the mice in that group. The mice showed a substantial reduction in weight benefit even after sixteen weeks.
Tempol isn’t hectic to the pores and skin but may be corrosive to the attention. Repetitive oral dosage of Tempol may also cause toxicity, although a single dosage has low to mild toxicity. Tempol danger and exposure are very low.
In general, acetaminophen (the active ingredient contained in Tempol) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.
Tempol is an excellent product for brain protection, decreasing heart risks, improves kidney function, protection against radiation, and many more benefits. It is a great supplementation for everyone. It is highly recommended for athletes, non-athletes, and bodybuilders out there.
References:
https://www.news-medical.net/news/20130925/Study-on-tempol-impacted-gut-bacteria-may-lead-to-new-treatments-for-obesity.aspx
https://www.ndrugs.com/?s=tempol&t=dosage
One reply on “TEMPOL”
Hi,
It would appear that your section about side effects does not refer to the correct Tempol. Tempol is also the name of an acetaminophen drug sold outside of the United States. This is not the same as 4-Hydroxy-TEMPO, the object of this article.