Methylene Blue
The traditional adult Dose for Methemoglobinemia is based on methemoglobinemia: 1 to two mg/kg intravenously. Must repeat after an hour if the supplement is essential. Inject intravenously very slowly over a length of numerous mins to save your neighborhood excessive concentration of the compound from generating extra methemoglobin.
Ordinary grownup Dose for Encephalopathy: Ifosfamide brought about encephalopathy (unlabeled use): (treatment may not be vital; encephalopathy may also enhance spontaneously)
Prevention: 50 mg each 6 to 8 hours
Treatment: 50 mg as an unmarried dose or each four to 8 hours till symptoms clear up
Methylene blue injection is used to deal with methemoglobinemia. It works by using converting methemoglobin to a more significant efficient kind of hemoglobin better to bring oxygen for the duration of the body.[1]
Methylene blue oral is used to deal with methemoglobinemia and urinary tract infections. It works as a mild antiseptic to kill bacteria inside the urinary tract.
You’ll most probably additionally receive an antibiotic medication to treat your infection.
Methylene blue is also used as a dye or staining agent to make sure body fluids and tissues simpler to view during surgical treatment or on an x-ray or other diagnostic exams.
Methylene blue will also be used for purposes now not listed in this medication manual.
How Does Methylene Blue Work?
While many texts suggest that methylene blue has oxidizing agent properties, its results as an oxidizing agent occur simplest at very high doses. At pharmacological doses, it has lowering agent houses.[1,3]
Its potency is attributable to this purpose; that is, methylene blue is used as a medicine for the treatment of methemoglobinemia. This may arise from the ingestion of certain prescription drugs, toxins, or vast beans.
Generally, through the NADH or NADPH established methemoglobin reductase enzymes, methemoglobin is decreased again to hemoglobin. While large quantities of methemoglobin arise secondary to pollutants, methemoglobin reductases are crushed.
Methylene blue, when injected intravenously as an antidote, is itself first decreased to leucomethylene blue, which then reduces the heme institution from methemoglobin to hemoglobin. Methylene blue can lessen the half-existence of methemoglobin from hours to mins. At excessive doses, however, methylene blue induces methemoglobinemia, reversing this pathway.
Why You Should Take: Methylene Blue The Benefits
Studies on the esophagus and continual gastritis were conducted. For the belly, intestinal metaplasia staining displays ninety-six-percent sensitivity and ninety-five percent specificity. For Barrett’s esophagus, Canto et al. (2002) demonstrated that unique intestinal metaplasia staining shows 95% sensitivity and ninety-seven percent specificity.
It has also been mentioned that less severe and somewhat abnormal methylene blue impregnation in a stained region suggests the presence of dysplasia (the dysplastic cells do not absorb the evaluation fabric as with ease) and may be used to manual biopsies. Different authors have contested this latter finding.
Potential Side Effects of Methylene Blue
On the side of its needed outcomes, methylene blue may also cause a few unwanted effects. Even though not all of these side consequences might also occur if they do occur, they may need scientific interest.
Test along with your medical doctor or nurse without delay if any of the following side effects occur at the same time as taking methylene blue: Agitation, bluish-colored lips, fingernails, or palms, confusion, cough, dark urine, diarrhea, trouble respiration, issue swallowing, dizziness or lightheadedness, and rapid heartbeat.
Where to Buy Online: Products Containing Methylene Blue
As people age, the cells in the body deteriorate, and hence some bodily functions and coordination are affected. Methylene blue is the best option to keep these functions intact and even treat the conditions that come with aging.[2]
Follow the link to find out where you can purchase methylene blue and also get more information about it.
Conclusion
Methylene blue, additionally referred to as methylthioninium chloride, is a medication and dye. As a medicine, it is specifically used to deal with methemoglobinemia. Specifically, it is used to treat methemoglobin levels, which might be extra than 30% or in which there are signs and symptoms, notwithstanding oxygen therapy. It has formerly been used for cyanide poisoning and urinary tract infections. However, this use is not encouraged. It’s far generally given through injection right into a vein.
References:
- Wikipedia (2018). Methylene blue. Available at: https://en.wikipedia.org/wiki/Methylene_blue
- PubChem (2005). Methylene Blue Anhydrous. Available at: https://pubchem.ncbi.nlm.nih.gov/compound/methylene_blue#section=Top
- Drugs, (2016). Methylene blue (injection). Available at: https://www.drugs.com/mtm/methylene-blue-injection.html